International Journal of Medical Sciences (IJMS)

Recurrent pregnancy loss RPL is characterized by at minimum 2 or 3 consecutive losses before the 20th week of gestation. In 1percentage to 5percentage of all pregnancies. Aim of the Work: assessing the effectiveness of low dosage aspirin and steroid therapy in the management of women with recurrent miscarriage vs. Aspirin and heparin LMWH study. Patients and Methods: In repeated miscarriage clinics, this randomized clinical experiment was performed in the Obstetrics and Gynecology Department, in Iraqi Hospital on 50 pregnant women, who fulfilled the inclusion criteria and after taking an informed consent. Group 1: included 25 pregnant females administered with low dose aspirin 75 mg tablet (one tablet twice daily) and prednisolone 5mg two tablets twice daily (20mg). Group 2: included 25 pregnant females administered with low dose aspirin 75 mg tablet (one tablet twice daily) and heparin. Both groups were followed in hospital recurrent miscarriage clinic every two weeks by ultrasonography from the incidence of the pregnancy till delivery. Results: Prednisolone (PSL) plus LDA increased the live birth rate by 32.2 percent compared to group II. and according to on-going pregnancy data was in group I 37/50(74%) and in group II 21/50(42%) OR (C.I. 95% 4.128 [2.142-7.952] RR (C.I. 95%1.875 [1.401-2.505] p<0.001, between the two groups, with a substantial differential. When it came to the development of contusion, there was a substantial variance (P<0.05). among the two groups. Conclusion: For women with idiopathic pregnancy loss, a combination of prednisone and low-dose aspirin could be a beneficial treatment.